- w3m inside of Emacs for browsing webpages in a fixed font format. This gives me all the Emacs goodness, along with a nice font and a beautiful background image - Firefox (with Firebug) for doing web development, this is tied into my Emacs with Mozex, so I can edit text fields C-M-e and view the source of whole webpages with C-M-u. - Opera with the text size set very large for most of my web browsing
Icicles is a mode for Emacs that allows for more sophisticated switching of buffers.
I graduated to iswitchb about 5 years ago, and I think it might be time to graduate again. I find iswitchb works really well for most projects, but these new Ruby on Rails projects that I'm working on require so many different files to be switched between that I find myself wanting something more.